Stent Surface Study

The gStent-BE standardized test stent has been used in surface characterization studies and to study drug coating and elution.  Martin McDermott and colleauges at the FDA recently published a paper investigating the drug coating process for coated drug-eluting stents (DES).  It was titled, “Application of Quality by Design (QbD) Approach to Ultrasonic Atomization Spray Coating of Drug-Eluting Stents” and appeared in the Journal AAPS PharmSciTech: An Official Journal of the American Association of Pharmaceutical Scientists (e-ISSN 1530-9932).

The image on the left is from their paper and shows the different surface roughnesses for four process variations on the gStent-BE.